Spermidine 98%

Spermidine Powder Supplier 

Yangge Biotech specializes in bulk spermidine powder research, production, testing, and sales. Our spermidine is produced through plant extraction and bio-fermentation, available as a white powder with 1% and 98% assay specifications. It is ultra-pure, 100% plant-based, and derived from high-quality wheat germ extract for optimal bioavailability. All products are manufactured in rigorously tested facilities and meet strict quality standards. We offer high quality at competitive prices. Welcome to inquire: info@yanggebiotech.com

What Is Spermidine 98%?

Spermidine 98% has the chemical structure formula C7H19N3. It comprises one amine group (NH) and two amino groups (NH2). Its molecular formula is shown below. It belongs to a colorless transparent crystal. Spermidine contains three nitrogen atoms in its chemical structure. Bulk spermidine powder has certain chemical and biological activities.

COA:

Spermidine 98% Source

spermidine 98% powder is found in many foods. It is especially high in legumes, whole grains, fermented foods, mushrooms, and some fruits. The body can synthesize spermidine itself. This takes place mainly in the liver, kidneys, and small intestine. However, the amount of spermidine produced by the body itself is affected by age, diet, gut microbiota genetic factors, etc. The amount of spermidine synthesized by the body itself begins to decline after the age of 30, and the decline becomes more pronounced after the age of 40.

Extraction Methods:

Yangge Biotech uses two methods to extract spermidine powder has two processes: plant extraction and bio-fermentation. Nowadays, the spermidine products on the market are mainly extracted from rice or wheat germ as raw material.

1. Plant-extracted spermidine

Plant-derived spermidine (Spermidine) production method is a method of extracting spermidine by physical and chemical means using natural plants as raw materials.

•Raw material selection and pretreatment:

The first step of plant-derived spermidine is to select the appropriate plant raw material. We use wheat germ, which is rich in spermidine. The quality of the raw material directly affects the purity and yield of the final extract, so it needs to be strictly screened and tested. After selecting the raw material, it must be pre-treated by washing, drying, and crushing.

•Solvent extraction:

The pre-treated plant powder needs to be extracted using a suitable solvent. The purpose of this step is to dissolve bulk spermidine powder from the plant matrix. During the extraction process, temperature, pH, and time need to be controlled.

•Purification and concentration:

The extracted solution contains a variety of plant compounds. This requires a multi-step purification process to isolate and concentrate spermidine. Commonly used purification methods include membrane filtration, ion exchange chromatography, and liquid-liquid extraction. These methods can effectively remove impurities and improve the purity of bulk spermidine powder. Subsequently, the extract must be concentrated by evaporation, lyophilization, etc.

•Detection and quality control:

The extracted and purified bulk spermidine powder needs to undergo rigorous quality testing. Commonly used detection methods include high-performance liquid chromatography (HPLC) and mass spectrometry. These detection techniques can accurately determine the content of spermidine and detect the level of impurities in it.

•Packaging:

The packaging process requires strict control of environmental conditions to prevent degradation and contamination of spermidine. After packaging, the product undergoes a final quality inspection.

Advantages of Yangge spermidine powder

•naturalness:

Plant-extracted spermidine is derived from natural plants and has high safety and biocompatibility. Compared with chemically synthesized spermidine, plant-extracted products are more in line with modern consumers' pursuit of natural and healthy products.

•Diversity:

Plants are rich in a variety of beneficial bioactive substances. In addition to bulk spermidine powder, it may also contain other ingredients that are beneficial to health. Such as antioxidants, vitamins, etc. Therefore, plant-derived spermidine products may have a wider range of health effects.

•Environmental friendliness:

The plant extraction process usually uses milder solvents and techniques. This reduces environmental pollution. The plant extraction process is more environmentally friendly than the chemical synthesis method.

2. Biological Fermentation of Spermidine

Biofermented bulk spermidine powder involves the cultivation of microorganisms, fermentation, and extraction.

(1)Production Process

•Strain Selection:

The production of fermented spermidine first requires the selection of a suitable microbial strain. Microorganisms that are capable of synthesizing spermidine in large quantities are usually selected. These strains are genetically modified or naturally selected to produce spermidine efficiently.

•Fermentation culture:

After selecting a suitable strain, it is placed in a fermenter for cultivation. During fermentation, the microorganisms convert nutrients in the medium into spermidine by metabolic action. Fermentation conditions such as temperature, pH, oxygen supply, and medium composition have a direct effect on the yield of spermidine, so precise control is required.

•Extraction and purification:

After fermentation is completed, bulk spermidine powder needs to be extracted from the fermentation broth. We usually use centrifugation to remove the bacteria and impurities. Then, further purification through liquid chromatography and other techniques, and finally high purity spermidine.

•Concentration and drying:

The purified spermidine solution usually needs to be concentrated and then converted into a powdered product by techniques such as spray drying or freeze drying, so that it can be easily preserved and transported.

(2)Advantages

•Natural source:

Biofermented spermidine is produced through the natural metabolism of microorganisms. It is closer to a natural source than chemically synthesized methods, reducing the risk of chemical contamination and residues.

•Efficient Production:

Advances in modern biotechnology allow the fermentation process to produce high concentrations of bulk spermidine powder in a relatively short period. By optimizing the strain and fermentation conditions, the production efficiency is greatly improved.

•High purity:

Through a rigorous purification process, the purity of bio-fermented spermidine is usually high. This can meet the requirements of food supplements and pharmaceutical applications.

•Environmentally friendly:

The fermentation process generally does not require the use of harmful chemicals. The production process produces less waste and it has less impact on the environment.

•High safety:

Due to the strict control of the bulk spermidine powder production process, bio-fermented spermidine is usually highly safe and suitable for long-term consumption.

Spermidine 98% Functions

1. Inhibition of Neuronal NOS: It can inhibit neuronal nitric oxide synthase (nNOS), an enzyme responsible for the production of nitric oxide in neurons. This helps regulate nitric oxide levels in the brain, which are crucial for neuronal signaling and function.

2. DNA Binding and Stabilization: Has the ability to bind and stabilize DNA molecules. It can interact with the negatively charged phosphate groups of DNA, neutralizing their charge and promoting DNA condensation and stability.

3. Stimulation of Enzymatic Activity: Stimulating the activity of enzymes like T4 polynucleotide kinase, which is involved in DNA repair and replication.

4. Anti-Aging Effects: Recent studies have suggested that it may have anti-aging effects. It can induce autophagy, a cellular process that helps remove damaged or dysfunctional proteins and organelles, promoting cellular rejuvenation.

5. Cancer Prevention: It has been shown to reduce the risk of cancer development. It can suppress tumor growth and enhance antitumor immune responses.

What Is Spermidine 98% Used For?

Spermidine 98% powder has gained attention for its potential health benefits and has been used in dietary supplements, cosmetics, and pharmaceuticals.

● In dietary supplements
Spermidine 98% powder is marketed as an anti-aging product. It is claimed to stimulate autophagy, a cellular process that removes damaged or unnecessary components, which is believed to promote longevity and prevent age-related diseases. Spermidine supplements are also marketed to support cardiovascular health, brain function, and hair growth.

● In cosmetics
It has been incorporated into skincare products for its potential anti-aging properties. It is claimed to rejuvenate the skin by enhancing cell renewal and promoting collagen production.

● In pharmaceuticals
It has shown promise in various studies for its potential to treat or prevent neurodegenerative diseases, and age-related disorders. It has demonstrated anti-inflammatory and antioxidant properties, which may help to protect against oxidative stress and cellular damage.

Tips On Improving Spermidine Levels

1. Dietary Intake of Spermidine-Rich Foods

Incorporate foods high in spermidine into your diet, such as aged cheese, soybeans, peanuts, wheat germ, and whole grains. These foods naturally contain it and can help increase its levels in the body.

Consume fermented foods like kimchi, sauerkraut, and yogurt, as the fermentation process often results in increased content.

Incorporate a variety of fruits and vegetables into your diet, as some contain spermidine precursors that can be converted by the body.

2. Lifestyle Modifications

Exercise regularly. Moderate to high-intensity exercise has been linked to increased levels. Cardiovascular exercises like running, swimming, and cycling are good choices.

Reduce stress levels. Chronic stress can negatively impact levels. Incorporate stress-reduction techniques like meditation, yoga, and deep breathing exercises into your daily routine.

Maintain a healthy weight. Obesity has been associated with lower levels. Adopt a balanced diet and regular exercise to maintain a healthy weight.

Quit smoking and limit alcohol consumption. These habits can negatively impact levels and overall health.

3. Supplementation

Consider taking spermidine supplements. While dietary sources are preferred, supplements can be a viable option for individuals who have difficulty incorporating spermidine-rich foods into their diet.

When choosing a supplement, ensure it comes from a reputable source and is certified for quality and purity.

Follow the recommended dosage instructions on the supplement label and consult a healthcare professional if you have any questions or concerns.

4. Other Considerations

Increase your intake of antioxidants. Antioxidants can help protect spermidine from oxidative damage, maintaining its stability and bioavailability. Foods rich in antioxidants include berries, nuts, and dark chocolate.

Drink plenty of water. Staying hydrated is essential for maintaining optimal levels and overall health.

Consider taking a probiotic supplement. Probiotics can help support a healthy gut microbiota, which may contribute to increased production.

Remember, improving spermidine levels is a gradual process that requires consistency and patience. Adopting a healthy diet, lifestyle, and supplementation plan can help you achieve your goals and maintain optimal levels for overall health and well-being.

Company Introduction And Certificates Obtained

Yangge Biotech Co., Ltd. focuses on natural plant extracts for food and beverages, dietary supplements and super food. Professional Spermidine 98% suppliers We are ISO, HACCP, Kosher and Halal certified. We have dedicated R&D and production teams, as well as 24-hour online services, and are committed to providing customers with innovative, high-quality raw material solutions to meet market needs.

Yangge Biotech certificates

Over the years, we have been committed to the product manufacture optimization and quality system establishment. And we have obtained the Certificate for Spermidine 98% Powder and all our manufactured products.

Third Part Test Result

We have established partnerships with prestigious third-party laboratories, including Eurofins and SGS. Upon customer request, we are capable of arranging reinspection of Spermidine 98% powder samples prior to shipment. Furthermore, we are fully equipped to coordinate testing with any laboratory designated by the customer to ensure their specific requirements are met.

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OEM Packaging Available

FAQ

※ Do you have factory?

Yes, we have a 1500m2 factory with modern equipment, welcome to visit our factory. When you have the details schedule, please kindly let me know in advance.

※ Do you have GMP?

All of our products are produced according to GMP standard, meanwhile, we have obtained ISO22000, Halal Certificate and so on.

※ What is your delivery time?

As usual, our delivery time is about 1~3 days after receipt of payments, however, for some special products, please kindly confirm with your sales manager in advance.

※ How can you confirm your quality?

Each batch of the goods can be shipped to you after strict inspection, if you still doubt, we can arrange the Pre-shipment Samples to your testing or to your pointed third party for retesting in advance, successfully, then we will arrange the bulk goods to you immediately.

Technological Process

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Exhibitions

We often attend international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.

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Yangge Biotech Factory

- All goods are manufactured in GMP standard facilities.

- All goods are released after inspection by our independent laboratory or third party.

- All goods are transported by professional freight companies.

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For Spermidine 98% there are different specification for your choice, we can provide 10-30g of free samples, US warehouse in stock of 500kg of each month for the market of the global. certificate of analysis (COA), MSDS, specification sheet, pricing quotation is obtainable upon your request.

If you have any question or need any documents, welcome to contact us by e-mail: info@yanggebiotech.