Spermidine 1%


Product name: Spermidine 1%
Other name: N-(3-Aminopropyl)-1,4-butanediamine;SpermidineN-(3-Aminopropyl)-1,4-butanediamine;4-azaoctamethylenediamine
Molecular formula: C7H22N3
Molecular weight: 148.29
Purity: 1%
Appearance: yellowish powder
No Irradiation, Non-GMO, Non-Allergen
Cooperation with famous laboratory for retesting
Min Order: 1Kg
Storage: Store in tightly closed original container, protected from light
Package: 1Kg/Aluminum foil bag or Custom Required
Inventory: 500Kg ~1000Kg
Brand Name: Yangge
  • Fast Delievery
  • Quality Assurance
  • 24/7 Customer Service
Product Introduction

Spermidine Powder Supplier 

Yangge Biotech specializes in bulk spermidine powder research, production, testing, and sales. Our spermidine is produced through plant extraction and bio-fermentation, available as a white powder with 1% and 98% assay specifications. It is ultra-pure, 100% plant-based, and derived from high-quality wheat germ extract for optimal bioavailability. All products are manufactured in rigorously tested facilities and meet strict quality standards. We offer high quality at competitive prices. Welcome to inquire: info@yanggebiotech.com

What Is Spermidine 1%?

Spermidine is a naturally occurring polyamine compound extracted from wheat germ, recognized for its role in supporting cellular health and longevity. spermidine has gained global attention as a functional ingredient that promotes autophagy— the body’s natural cell renewal process. Our Spermidine Powder is standardized to 1% active content and is available as a fine brown yellow powder. 

As one of the most promising ingredients in the anti-aging and biohacking markets, Spermidine is widely used in nutraceuticals, functional foods, and wellness supplements. It offers a scientifically backed approach to supporting metabolic function, healthy aging, immune balance, and cognitive health.

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WITH:

Test Items

Specification

Result

NO

Appearance

White to off-white powder

Off-White Powder

Visual

Purity

≥98%

99.0%

GC

Solubility

Soluble in water

Conform

CP2020

Loss on drying

≤1.0%

0.28%

CP2020

Residue on ignition

0.2%

0.02%

CP2020

Ethanol(GC)

5000ppm

600ppm

GC

Heavy Metal Content

Pb

≤0.1 ppm

Conform

GB5009

Hg

≤0.1ppm

Conform

GB5009

Cd

≤0.2 ppm

Conform

GB5009

As

≤0.1ppm

Conform

GB5009

Total microbial count

≤500CFU/g

<10

GB4789

Coliform

≤0.92 MPN/g

Conform

GB4789

Mold and yeast

≤50CFU/g

Conform

GB4789

Staphylococcus aureus

0/25g

Conform

GB4789

Salmonella

0/25g

Conform

GB4789

Conclusion

All inspection items are in conformity with the specifications.

Storage Condition

Sealed packaging, stored at cool, dry, and away from light.

Spermidine 98% Source

spermidine 98% powder is found in many foods. It is especially high in legumes, whole grains, fermented foods, mushrooms, and some fruits. The body can synthesize spermidine itself. This takes place mainly in the liver, kidneys, and small intestine. However, the amount of spermidine produced by the body itself is affected by age, diet, gut microbiota genetic factors, etc. The amount of spermidine synthesized by the body itself begins to decline after the age of 30, and the decline becomes more pronounced after the age of 40.

Extraction Methods:

Yangge Biotech uses two methods to extract spermidine powder has two processes: plant extraction and bio-fermentation. Nowadays, the spermidine products on the market are mainly extracted from rice or wheat germ as raw material.

1. Plant-extracted spermidine

Plant-derived spermidine (Spermidine) production method is a method of extracting spermidine by physical and chemical means using natural plants as raw materials.

•Raw material selection and pretreatment:

The first step of plant-derived spermidine is to select the appropriate plant raw material. We use wheat germ, which is rich in spermidine. The quality of the raw material directly affects the purity and yield of the final extract, so it needs to be strictly screened and tested. After selecting the raw material, it must be pre-treated by washing, drying, and crushing.

•Solvent extraction:

The pre-treated plant powder needs to be extracted using a suitable solvent. The purpose of this step is to dissolve bulk spermidine powder from the plant matrix. During the extraction process, temperature, pH, and time need to be controlled.

•Purification and concentration:

The extracted solution contains a variety of plant compounds. This requires a multi-step purification process to isolate and concentrate spermidine. Commonly used purification methods include membrane filtration, ion exchange chromatography, and liquid-liquid extraction. These methods can effectively remove impurities and improve the purity of bulk spermidine powder. Subsequently, the extract must be concentrated by evaporation, lyophilization, etc.

•Detection and quality control:

The extracted and purified bulk spermidine powder needs to undergo rigorous quality testing. Commonly used detection methods include high-performance liquid chromatography (HPLC) and mass spectrometry. These detection techniques can accurately determine the content of spermidine and detect the level of impurities in it.

•Packaging:

The packaging process requires strict control of environmental conditions to prevent degradation and contamination of spermidine. After packaging, the product undergoes a final quality inspection.

Spermidine flow chart

Advantages

•Natural source:

Biofermented spermidine is produced through the natural metabolism of microorganisms. It is closer to a natural source than chemically synthesized methods, reducing the risk of chemical contamination and residues.

•Efficient Production:

Advances in modern biotechnology allow the fermentation process to produce high concentrations of bulk spermidine powder in a relatively short period. By optimizing the strain and fermentation conditions, the production efficiency is greatly improved.

•High purity:

Through a rigorous purification process, the purity of bio-fermented spermidine is usually high. This can meet the requirements of food supplements and pharmaceutical applications.

•Environmentally friendly:

The fermentation process generally does not require the use of harmful chemicals. The production process produces less waste and it has less impact on the environment.

•High safety:

Due to the strict control of the bulk spermidine powder production process, bio-fermented spermidine is usually highly safe and suitable for long-term consumption.

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Benefits of Spermidine 1% Powder

  • Anti-Aging Compounds

Spermidine is a polyamine found in the body which produces the anti-aging process of autophagy. Levels naturally decrease as we age. Polyamine levels can be increased by including spermidine-rich foods or supplements.

  • Improves Memory Loss

Spermidine helps dissolve amyloid-beta proteins through autophagy. These protein plaques can build up in the brain and are thought to be related to memory loss.

  • Reduce the Risk of Cancer

Studies have suggested that an increase in the nutritional uptake of the natural polyamine spermidine may be associated with reduced overall cancer-specific mortality.

  • Triggers Autophagy

Spermidine induces autophagy, the process of cellular rejuvenation. Autophagy regulates cellular metabolism and balances nutrients during cell stress.

  •  Assists in Cellular Growth

Spermidine polyamines can bind to many different types of molecules supporting processes like cell growth. Spermidine also appears to function as a factor during cell division, which is important for healthy tissue growth and function.

  • Decrease Oxidative Stress

Spermidine induced autophagy helps cells reuse their old or damaged organelles to attain cellular renewal. This limits inflammation and oxidative stress, the main culprits involved in aging and related diseases.

  • Minimize Heart Disease

Aging leads to the stiffening of the heart muscles. This can potentially increase cardiovascular system failure. Spermidine may prevent that by helping increase the elasticity of the heart muscle.

Spermidine itself is the active ingredient in spermidine supplements.

spermidine autophagy

Applications of Spermidine 1% Powder

Spermidine is increasingly used in premium longevity supplements and cellular wellness products. It is commonly formulated into capsules, powders, drink mixes, and tablets that support autophagy activation, cardiovascular function, cognitive performance, and skin regeneration.

In addition to its use in dietary supplements, Spermidine is gaining traction in the biohacking, wellness, and anti-aging markets due to its ability to influence gene expression, mitochondrial function, and inflammation response. Its wheat germ origin also appeals to formulators focused on natural, plant-based solutions.

● In dietary supplements
Spermidine 98% powder is marketed as an anti-aging product. It is claimed to stimulate autophagy, a cellular process that removes damaged or unnecessary components, which is believed to promote longevity and prevent age-related diseases. Spermidine supplements are also marketed to support cardiovascular health, brain function, and hair growth.

● In cosmetics
It has been incorporated into skincare products for its potential anti-aging properties. It is claimed to rejuvenate the skin by enhancing cell renewal and promoting collagen production.

● In pharmaceuticals
It has shown promise in various studies for its potential to treat or prevent neurodegenerative diseases, and age-related disorders. It has demonstrated anti-inflammatory and antioxidant properties, which may help to protect against oxidative stress and cellular damage.

Spermidine is a natural polyamine

Company Introduction And Certificates Obtained

Yangge Biotech Co., Ltd. focuses on natural plant extracts for food and beverages, dietary supplements and super food. Professional Spermidine 98% suppliers We are ISO, HACCP, Kosher and Halal certified. We have dedicated R&D and production teams, as well as 24-hour online services, and are committed to providing customers with innovative, high-quality raw material solutions to meet market needs.

Yangge Biotech certificates


Over the years, we have been committed to the product manufacture optimization and quality system establishment. And we have obtained the Certificate for Spermidine 1% Powder and all our manufactured products.

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Third Part Test Result


We have established partnerships with prestigious third-party laboratories, including Eurofins and SGS. Upon customer request, we are capable of arranging reinspection of Spermidine 1% powder samples prior to shipment. Furthermore, we are fully equipped to coordinate testing with any laboratory designated by the customer to ensure their specific requirements are met.

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OEM Packaging Available


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FAQ


※ Do you have factory?

Yes, we have a 1500m2 factory with modern equipment, welcome to visit our factory. When you have the details schedule, please kindly let me know in advance.

※ Do you have GMP?

All of our products are produced according to GMP standard, meanwhile, we have obtained ISO22000, Halal Certificate and so on.

※ What is your delivery time?

As usual, our delivery time is about 1~3 days after receipt of payments, however, for some special products, please kindly confirm with your sales manager in advance.

※ How can you confirm your quality?

Each batch of the goods can be shipped to you after strict inspection, if you still doubt, we can arrange the Pre-shipment Samples to your testing or to your pointed third party for retesting in advance, successfully, then we will arrange the bulk goods to you immediately.

Technological Process


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Exhibitions


We often attend international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.

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Yangge Biotech Factory


- All goods are manufactured in GMP standard facilities.

- All goods are released after inspection by our independent laboratory or third party.

- All goods are transported by professional freight companies.

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For Spermidine 1% there are different specification for your choice, we can provide 10-30g of free samples, US warehouse in stock of 500kg of each month for the market of the global. certificate of analysis (COA), MSDS, specification sheet, pricing quotation is obtainable upon your request.

If you have any question or need any documents, welcome to contact us by e-mail: info@yanggebiotech.

 

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