Polydeoxyribonucleotide (PDRN)

What Is A Polydeoxyribonucleotide?

Polydeoxyribonucleotide powder (PDRN) is a biologically active polynucleotide mixture, and its main source is the sperm cells of salmon (Oncorhynchus keta). Through precise extraction and purification technology, DNA fragments that meet specific specifications can be obtained. 

Polydeoxyribonucleotide (PDRN) is a DNA-derived compound often used in regenerative medicine, wound healing, and aesthetic treatments. It consists of small DNA fragments that help stimulate tissue repair, reduce inflammation, and promote cell growth. A large number of previous studies have confirmed that PDRN has strong biological properties and has shown significant effects in anti-inflammatory repair, optimizing skin texture, and promoting tissue regeneration. Therefore, it has attracted much attention in the fields of biomedicine and beauty skin care.

Specification

Yangge Biotech Polydeoxyribonucleotide Powder Feature

1. High-purity 90% PDRN from salmon DNA

2. Clinically backed skin regeneration and tissue repair properties

3. Promotes cell proliferation, collagen synthesis, and wound healing

4. Water-soluble, easy to formulate into cosmeceutical or injectable products

5. Free from harmful additives or preservatives

6. Certified organic and clean-label friendly

Quality & Compliance

Our PDRN Powder is manufactured under pharmaceutical-grade quality standards:

1. Production in ISO22000-certified, GMP-compliant facilities

2. Purity verified by HPLC and third-party analysis

3. Sterility, heavy metal, and endotoxin tests conducted on all batches

Certifications:

1. KOSHER, HALAL

2. HACCP, ISO22000

3. EU Organic & USDA Organic

4. COA (Certificate of Analysis) available upon request

5. Full traceability and documentation support

Test report

PDRN contains 50% double-stranded deoxyribonucleotides, and the two polydeoxyribonucleotides are connected by hydrogen bonds between base pairs [adenine (A) = thymine (T); guanine (G) = cytosine (C)], eventually forming a double helix structure (as shown in Figure 1).

The base composition of PDRN is as similar as 98% to human DNA. Based on this biological effect, its clinical application range has gradually expanded, and it has shown significant effects in tissue repair, wound healing, anti-ischemia, and anti-inflammation.

Polydeoxyribonucleotide Benefits:

1. Promote wound recovery
It can quickly generate capillaries, provide nutrients and oxygen, clear wounds, and help wound recovery.

2. Promote cell growth
It can promote the secretion of cell growth factors to stimulate cell growth.

3. Anti-inflammatory
PDRN Polydeoxyribonucleotide has the function of stimulating the regeneration of collagen and elastic fibers and has a good anti-inflammatory effect. It also has obvious effects on the regeneration and repair of human skin, ligaments and tendons.

4. Protect against UV damage
Because people need to go out to work or play every day, human skin will continue to be exposed to ultraviolet rays, which can cause DNA damage and skin aging. Studies have found that PDRN can protect cells from UV-induced DNA damage, thereby achieving a whitening effect.

5. Reduce melanin production
Melanin can easily cause various skin problems and pigmentation, and the production of melanin is regulated by melanin-generating enzymes, including tyrosinase, tyrosinase-related protein 1, and polychromatic tautomerase.

6. Antioxidant
PDRN has antioxidant activity, which can promote collagen synthesis and inhibit the oxidative stress response of skin cells, and its antioxidant activity is dose-dependent.

Applications Of PDRN With Different Molecular Weights:

1. Cosmetics

700 KDa and above are used for skin regeneration, joint cartilage regeneration and bone formation promotion; Improve wrinkles, regenerate and anti-aging, repair stretch marks, whiten and remove spots

2. Pharmaceuticals

50~500 KDa are used in pharmaceutical treatment to achieve tissue regeneration, corneal regeneration and treatment of musculoskeletal diseases; Tissue regeneration, corneal regeneration, musculoskeletal treatment, cardiovascular and cerebrovascular treatment

3. Medical devices

40~60 KDa are used in cosmetics and foods to achieve barrier repair, wrinkle improvement and skin beauty. Skin regeneration, promote bone progression, joint cartilage regeneration, diabetic foot ulcer treatment

4. Food

Improve digestive environment, enhance immunity, delay aging

Where To Buy Polydeoxyribonucleotide powder (PDRN)?

Discover the exceptional quality of Polydeoxyribonucleotide powder (PDRN) from YANGGE BIOTECH INGREDIENTS, available with a complimentary sample at yanggebiotech.com. Renowned as an industry leader, YANGGE BIOTECH is dedicated to manufacturing and distributing premium-grade dietary supplement ingredients, delivering purity and potency with every product.

Not only does YANGGE BIOTECH serve health-conscious consumers directly, but it also partners with top brands across the food and supplement sectors, supplying raw, pure ingredients that meet the highest industry standards. Elevate your product offerings or personal wellness with our trusted ingredients—reach out to us today to place your order and experience the YANGGE difference.

Third Part Test Result

We have established partnerships with prestigious third-party laboratories, including Eurofins and SGS. Upon customer request, we are capable of arranging reinspection of NAD (Nicotinamide Adenine Dinucleotide) samples prior to shipment. Furthermore, we are fully equipped to coordinate testing with any laboratory designated by the customer to ensure their specific requirements are met.

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OEM Packaging Available

Yangge Biotech Halal certificates

Over the years, we have been committed to the product manufacture optimization and quality system establishment. And we have obtained the Certificate for Polydeoxyribonucleotide powder (PDRN) and all our manufactured products.

FAQ

※ Do you have factory?

Yes, we have a 1500m2 factory with modern equipment, welcome to visit our factory. When you have the details schedule, please kindly let me know in advance.

※ Do you have GMP?

All of our products are produced according to GMP standard, meanwhile, we have obtained ISO22000, Halal Certificate and so on.

※ What is your delivery time?

As usual, our delivery time is about 1~3 days after receipt of payments, however, for some special products, please kindly confirm with your sales manager in advance.

※ How can you confirm your quality?

Each batch of the goods can be shipped to you after strict inspection, if you still doubt, we can arrange the Pre-shipment Samples to your testing or to your pointed third party for retesting in advance, successfully, then we will arrange the bulk goods to you immediately.

Technological Process

Exhibitions

We often attend international exhibitions, including CPhI, FIC, API, Vitafoods, SupplesideWest.

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Yangge Biotech Factory

- All goods are manufactured in GMP standard facilities.

- All goods are released after inspection by our independent laboratory or third party.

- All goods are transported by professional freight companies.

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For Polydeoxyribonucleotide powder (PDRN) there are different specification for your choice, we can provide 10-30g of free samples, US warehouse in stock of 500kg of each month for the market of the global. certificate of analysis (COA), MSDS, specification sheet, pricing quotation is obtainable upon your request.

If you have any question or need any documents, welcome to contact us by e-mail: info@yanggebiotech.com